Watch our first behind-the-scenes video featuring the R&D Laboratory in our Oak Harbor facility. Hear our testing specialist, Troy Sanders, discuss how we helped a customer solve a ceramic-on-ceramic valve aspiration issue in their system!
Solutions To The Common ‘Bubble Problem’ (Part 3)
From my previous post, we saw that bubbles can form from cavitation during dispensing due to excess dissolved gas, or to low pressure areas and turbulence during dispensing. Sometimes bubbles form despite the best efforts of instrument engineers to eliminate dissolved atmosphere. Unfortunately, bubbles can show up long after an instrument is designed and placed into service. Even the most well-thought-out designs can encounter strange, unexplainable, errors. The following is an example of such a situation and its solution. Three years ago, a customer came to IDEX Health & Science with a problem: they were encountering a build-up of bubbles…[Read this article]
Degassing: A Behind-The-Scenes Discussion
While working on our latest IDEX Health & Science engineering webinar, our fluidics experts had a lot to talk about. We captured a frank, behind-the-scenes discussion about real-life degassing considerations, and thought we’d pass it along! To sign up for the upcoming Degassing & Debubbling webinar, or to view our archived webinars, visit us here: http://www.idex-hs.com/about/webinar_video_library.aspx
Solutions To The Fundamental “Bubble Problem” Videos
As part of our ongoing series about the benefits of degassing and debubbling technology, we would like to share two videos that showcase our product offerings. Whether you are working with HPLC or low-pressure diagnostic applications, dissolved gases and bubbles in system liquids cause dispense volume anomalies in many instruments, negatively affecting both dispense precision and analytical accuracy. Now you have a choice of components for actively removing bubbles with or without also removing dissolved system gases. Online vacuum degassing offers operating convenience, high efficiency, and low operating costs compared to other common degassing technologies. Watch to learn more about…[Read this article]
Solutions to the Fundamental “Bubble Problem” (Part 2)
Continuing where my previous blog post left off, it became obvious to early HPLC engineers that the mixing of solvents was problematic to designing these systems. Pure water or water-based fluidic systems were not thought to have a real need for the removal of air from fluids and reagents in their systems. In fact, early bioanalyzers utilized air segmented streams of fluid moving through relatively large internal diameter tubes–a method known as segmented flow analysis. Systems like that generally disposed of the air bubble through various mechanisms, or simply ignored the portion of the detector signal related to the bubble….[Read this article]
Troubleshooting UHPLC Connection Challenges
As UHPLC has gained a solid foothold in the market, some of the problems that have plagued chromatographers – problems like band broadening, split peaks, carryover, etc. – have begun to occur with greater frequency. While numerous things may be contributing to these problems, one common thing is often overlooked: possible problems with the system’s tubing connections. Problem #1 – Tubing Slippage Because system pressures in UHPLC can exceed 15,000 psi (1,034 bar), the physical demands on the tubing connections can be very significant. Due to the higher pressures of UHPLC coupled with the pressure cycling that can occur in…[Read this article]